Rest and exercise hemodynamics after the Fontan procedure.

Sildenafil improves exercise hemodynamics in Fontan patients.

BACKGROUND Patients with Fontan circulation have reduced exercise capacity. The absence of a presystemic pump may limit flow through the pulmonary circulation, restricting ventricular filling and cardiac output. We evaluated exercise hemodynamics and the effect of sildenafil on exercise hemodynamics in Fontan patients. METHODS AND RESULTS Ten Fontan patients (6 men, 20±4 years) underwent card...

Arrhythmias after the Fontan procedure.

OBJECTIVE To study the determinants and outcome of arrhythmias after the Fontan type operation. DESIGN Retrospective analysis of data in patients operated on between 1972 and 1986 (follow up 5-19 years (mean 12 years)). PATIENTS All 60 patients undergoing a Fontan type procedure at the National Heart Hospital, London, during the study period (mean age (SD) 12.3 (6.8) years). RESULTS Posto...

Sildenafil Improves Exercise Hemodynamics in Fontan Patients Van De Bruaene et al: Sildenafil and Exercise Hemodynamics in Fontan Patients

Oxygen utilization and hemodynamic response during exercise in children after Fontan procedure.

Eight patients, 9.1 to 16.5 years of age, were studied 2.8 to 8.5 years after Fontan operation. Oxygen utilization was determined during upright bicycle exercise. The cardiac index and stroke index were measured by echocardiography and the anaerobic threshold was determined. The results were compared with 10 patients after surgical closure of the atrial septal defect. Anaerobic threshold (AT) i...

Cardiac transplantation after the Fontan or Glenn procedure.

OBJECTIVES The purpose of this study was to review the clinical course and outcome of cardiac transplantation after a failed Glenn or Fontan procedure. BACKGROUND Late complications of the Glenn or Fontan procedure, including ventricular failure, cyanosis, protein-losing enteropathy, thromboembolism, and dysrhythmias often lead to significant morbidity and mortality. If other therapies are in...